Research Projects | ProfBeeduSashidhar

Extramurally Funded Research Projects & Consultancy Work

University Research Programme:

Co-ordinator: Department of Science & Technology Sponsored ‘Promotion of University Research & Scientific Excellence (PURSE-I) programme (2011-2015, with a sanctioned grant of Rs. 90 millions; PURSE-II, 2017-21, with a sanctioned grant of Rs. 81 millions).

Co-ordinator: Centre with Potential for Excellence in ‘Bioprospecting of Certain Medicinal Plants for Health Care’ (UGC Sponsored Programme- 2012-17, with a sanctioned grant of Rs. 28 millions).

A. Research projects: completed and ongoing:

1. Project title: Evaluation of silvernano-biocomposite material as an anti-fungal agent in relation to aflatoxin production

Principal Investigator: B. Sashidhar Rao

Funding Agency: Council of Scientific & Industrial Research, New Delhi.

Duration and Funding: 2012-2015, Rs. 17,77,000/-

Status: Completed.

2. Project title: Immunoanalytical detection and validation of transgenic Cry 1Ac protein, as a measure of food safety.

Principal Investigator: R. Karuna

Co PI: B. Sashidhar Rao

Funding Agency: University Grants Commission, New Delhi.

Duration and Funding: 2011-2015; Rs. 15,00,000/-

Status:Completed.

3. Project title: Gum kondagogu nano-composite: A carbohydrate polymer based nanoparticles for efficient uranium removal from radioactive waste.

Principal Investigator: B. Sashidhar Rao

Co PI: Karuna, R & VTP Vinod.

Funding Agency: Board of Research in Nuclear Sciences (BRNS), Department of Atomic Energy, Mumbai.

Duration and Funding: 2011-2014; Rs. 17,70,100/-

Status: Completed.

4. Project Title: Digital-Image based detection of chitin as an index fungal contamination in agricultural commodities.

Principal Investigator: B. Sashidhar Rao.

Funding Agency: Council of Scientific & Industrial Research, New Delhi.

Duration and Funding: 2007-2010, Rs. 10,00,000/-

Status: Completed.

5. Project Title: Immunochemical Approach to Cataractogenesis: Use of Advanced glycated end products (AGEs) of Lens crystallins as a biomarker.

Principal Investigator: B. Sashidhar Rao; Co-investigator: K. Seetharam Bhat.

Funding Agency: Department of Biotechnology, New Delhi.

Duration and Funding: 2003-2006, Rs. 13,00,000/-

Status: Completed.

6. Project Title: Screening of antiafla-toxigenic compounds from neem-seed kernel extracts in relation to fungal infestation and aflatoxin elaboration in high risk agricultural commodities.

Principal Investigator: B. Sashidhar Rao.

Funding Agency: Council of Scientific & Industrial Research, New Delhi.

Duration and Funding: 2002-2004, Rs. 9,88,000/-. Status: Completed.

7. Project Title: Biological effects of magnetic fields.

Investigators : B. Sashidhar Rao and C. Subramanyam.

Funding Agency: Central Power Research Institute, Hyderabad.

Duration and Funding: 1999-2002, Rs. 35,00,000/-

Status: Completed.

8. Project Title: Biological monitoring of Aflatoxins: Development of an immunoanalytical method for the detection of aflatoxin B1-protein adduct as a biomarker for aflatoxin exposure.

Principal Investigator: B. Sashidhar Rao.

Funding Agency: Department of Biotechnology, New Delhi.

Duration and Funding: 1997-2000, Rs. 8,78,000/-

Status: Completed.

9. Project Title: Biological effects of ultra high voltage (UHV) fields.

Investigators : B. Sashidhar Rao and C. Subramanyam.

Funding Agency: Central Power Research Institute, Hyderabad.

Duration and Funding: 1996-2000, Rs. 28,00,000/-. Status: Completed.

10. Project Title: Development and application of simple test kits for pesticide residues in foods: establishment of the capacity to develop and produce assays in India (Indo-Australian project). International Project

Principal Investigator: B. Sashidhar Rao.

Funding Agency: Australian Centre for International Agricultural Research, Australia.

Duration and Funding: 1996-1998, A$ 12,160/-.

Status: Completed.

11. Project Title: Development of an immunoanalytical method for the detection of Aflatoxin B1-N7-Guanine adduct and its field application: A tool for molecular epidemiology.

Principal investigator: B. Sashidhar Rao

Funding Agency: Department of Science & Technology, New Delhi.

Duration and Funding: 1994-98, Rs. 17,86,560/-.

Status: Completed.

12. Project Title: RIA for Buffalo ferritin.

Principal investigator: Vijay Deshpande

Co-investigator: B. Sashidhar Rao.

Funding Agency: Department of Atomic Energy (DAE), Bombay

Duration and Funding: 1993-95, Rs. 4,60,000/-.

Status: Completed.

13. Project title: Dip-Strip method for Aflatoxin analysis: Development of a portable aflatoxin detection kit (AFLAKIT).

Principal Investigator: B. Sashidhar Rao.

Funding Agency: Council of Scientific & Industrial Research (CSIR), New Delhi.

Duration and Funding: 1991-92, Rs. 1,55,000/-.

Status: Completed.

14. Project title: Development of homogeneous enzyme assay for detection of Aflatoxin B1.

Principal investigator: B. Sashidhar Rao.

Funding Agency: Indian Council of Medical Research, New Delhi.

Duration and Funding: 1990-1993, Rs 1,20,000/-.

Status: Completed.

DST, New Delhi -Sponsored Research projects to my lab, under the DST-Women Scientist Scheme (A/B) & SERB-YSS Research Scheme.

1. Project title: Novel biopolymer Gum Kondagogu (Cochlospermum gossypium) based nanocarrier matrix for delivery of selected anticancer drugs.

DST- Women Scientist Scheme A (WOS-A) fellowship awardee: Dr. K. Vani

Funding: Rs. 31,68,000/-

Duration: 2017-2020, Ongoing.

Project supervisor/Mentor: B. Sashidhar Rao.

2. Project title: Evaluation of anti-aflatoxigenic potentials of selected antifungal peptides.

DST-SERB-Young Scientist Scheme fellowship awardee: Dr. S. Manju Devi

Funding: Rs. 32,60,000/-

Duration: 2015-2018, Ongoing.

Project supervisor/Mentor: B. Sashidhar Rao.

3. Project title Development of ELISA methodology for detection of Cenirus cerebellris infection in sheep brain.

Women Scientist (B) awardee: Dr. Usha Rani.

Funding: Rs. 8,00,000/-

Duration: 2007-2009, Completed.

Project supervisor/Mentor: B. Sashidhar Rao.

4. Project title ELISA for aflatoxin B1-glutathione adducts in urine.

Women Scientist (A) awardee: Dr. Sujatha, N.

Funding: Rs. 17, 23,000/-

Duration: 2004-2007, Completed.

Project supervisor/Mentor: B. Sashidhar Rao

B. Consultancy Research Projects:

1. Consultancy project: Project Title: Screening of synthetic anti-fungal compounds:

Consultant: B. Sashidhar Rao

Funding Agency: FDC, (P) Ltd. Mumbai.

Duration and Funding: 2002-2003; Funding: Rs. 1,25,000/-

Status: Completed

2. Consultancy project: Project Title: Development of ELISA Kit for the detection of cobra venom in biological samples of human origin.

Consultant: B. Sashidhar Rao

Funding Agency: Andhra Pradesh Forensic Science Laboratory, Hyderabad.

Duration and Funding: 2003-04; Funding: Rs. 3,00,000/-.

Status: Completed.

3. Consultancy (international) project: Evaluation of groundnut cultivars for aflatoxin resistance. Project sponsored by International Crops Research Institute for Semi-Arid Tropics (ICRISAT), Potancheru, and ACIAR, Australia.

Principal investigators: Sashidhar RB & Subramanyam, C.

Consultancy funding: Rs. 2,00,000/-, 2004.

Status: Completed.

C. Industry Sponsored Ph.D. Programme:

Also undertaken Industry/Corporate sponsored research projects for Ph.D. programme, amounting to Rs. 3,18,000/-
Raasi Cements, Vishnupuram (Rs. 1,20,000/-), 1999-2002- On Botanical pesticide .
Krebs Biochemicals Ltd, Hyderabad, (Rs. 38,000/-), 2001-2002 – On Bt-toxin.
Apollo Hospital, Hyderabad (Rs. 2,40,000/-), 2002-2005.- Experimental Cataract.

D. Consultancy Service extended to Satyam Computers, Hyderabad on Pharma Domain Certificate Programme for IT professionals, under University-Industry HUB. Feb – April, 2006.

E. International/Industrial/Institutional/Consultancy Service:

1. Industry: Assessment of antimicrobial potential of Genopep-1peptide.

Funding Agency: Issar Pharma. Ltd. Hyderabad.

Duration and Funding:2011; Funding: Rs. 20,000/-

2. Industry: Preparation of Protocol for the detection of an anti-cancer peptide by ELISA.

Funding Agency: Issar Pharma. Ltd. Hyderabad.

Duration and Funding:2008; Funding: Rs. 12,000/-

3. Industry: (a) Shruthi Bulk Drugs (P) Ltd. Hyderabad, for cryo-processing of omeprozole (2001).

Funding: Rs. 5000

4. Consultant to Central Power Research Institute (Govt. of India) on Biological Effects of Ultra High Voltage Transmission Fields. (1996-2002).

Rs. 2,00,000.

5. Consultant to Central Food Technological Research Institute (CFTRI), Mysore, on immunoassays for pesticides (1996-97).

6. Consultant to Food and Agriculture Organization of the United Nations, Rome, for Joint FAO/UNEP Project on Training Network on Mycotoxin Control in Asia. (1993).

F. PRODUCT DEVELOPMENT:

Developed a multi-purpose, portable long wave UV lamp.

G. PATENT:

Indian patent filed on 31-12-2016; Patent Publication date: 13-01-2017.

Title of invention: Z-1-(p-dimethylaminoethoxyphenyl)-1, 2-diphenyl-1butene metabolite.

Patent application #: 201641045175